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IV vitamin B12 therapy is great for quick treatment in serious cases

JCI Insight 2021;6;e124985

thus, anaphylaxis in IgE-KO mice is probably due to OVA-specific IgG1 antibodies that are increased by allergic sensitization and does not require IgE (Extended Data Fig

5.3 Human evidence of transgenerational effects Although human data documenting transgenerational EED effects remain limited due to the extended timeframes required for multigenerational studies, emerging evidence provides preliminary support for intergenerational inheritance of reproductive impairments