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When this genomic breadth is cited to justify systemic GHK-Cu dosing the reasoning being that a molecule touching thousands of genes must be doing something profound throughout the body it is worth remembering that broad gene modulation is as plausibly a reason for caution as for enthusiasm, since specificity, not breadth, is usually what separates a useful therapeutic from an indiscriminate one

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Owing to its defined structure and copper-binding properties, GHK-Cu is commonly included in laboratory investigations involving peptide stability, metal coordination chemistry, and analytical method development

The interaction between pulsatile GH secretion and circadian clock system warrants further research