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Materials and methods Materials Human serum albumin (HSA), Bismuth nitrate (Bi[NO 3 ] 3 5H 2 O), Ethylene glycol (EG, 99%, Shanghai Chemical Reagent, China), and Potassium fluoride (KF2H 2 O) were purchased from Aladdin Reagent Co., Ltd

When blocking glucose metabolism, tumor cells rapidly adapt to metabolic inhibition by switching energy pathways (e.g., glutaminolysis or fatty acid oxidation), limiting the efficacy of glycolysis inhibitors like 2-DG or HK2-targeting agents [129]

A person with a sulfa allergy can experience severe complications

This gene targeting led to the creation of transgenic mice, or designer mice, that replicated human disease