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Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease

) Summary and Conclusions Genetic variation in folate metabolism has emerged as a critical area of investigation, not only for its role in rare hereditary disorders but for its far-reaching implications in common, multifactorial conditions such as cardiovascular disease, birth defects, cancer, and neurodevelopmental disorders