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This storage capacity means that deficiency symptoms often develop slowly, sometimes taking years to manifest after dietary intake becomes inadequate or absorption is compromised

When you take vitamins orally, they must pass through the digestive system, where absorption can be significantly reduced due to stomach acid breakdown, gut health issues, and metabolism

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[248] Further, the study participants had persistent chronic low back pain, lasting a minimum of 90 days of conservative medical management that included at least medication and physical therapy, and they were not considered candidates for spine surgery