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Hesperidin in Chronic Fatigue Syndrome: An Integrated Analysis of Traditional Pharmacology and Machine LearningBased Therapeutic Predictions ElShiekh 2025 Chemistry & Biodiversity Wiley Online Library Selective Small Molecule Activator of Patient Derived GPX4 Variant ACS Chemical Biology Frontiers Glutathione deficiency in the pathogenesis of SARS CoV 2 infection and its effects upon the host immune response in severe COVID 19 disease Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt Brown British Journal of Pharmacology Wiley Online Library

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Ultimately, while CQDs represent a highly versatile and multifunctional nanoplatform, their translational success will depend on systematic validation, standardised manufacturing, and stronger integration between fundamental research and clinical application [103]

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