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LC-MS-based metabolite detection For determination of the relative Cys and GSH pool sizes across compartments, previously established LC-MS conditions were employed 5,24 For chromatographic metabolite separation, a Vanquish UPLC system was coupled to a Q Exactive HF (QE-HF) mass spectrometer equipped with HESI (Thermo Fisher Scientific, Waltham, MA, USA)

Din MAU, Lin Y, Wang N, Wang B, Mao F

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These results suggest that PtNP disrupts the vicious cycle of inflammation, ROS generation, and degeneration with higher efficacy [170]