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However, aberrant glycosylation can also modify antigen processing and MHC loading, giving rise to glycopeptide neoantigens that are capable of engaging T-cell receptors (TCRs) in a distinct manner

L., Fernndez-Hernando, C., and Lamas, S

The efficacy of once-weekly subcutaneous semaglutide and once-daily oral semaglutide has been investigated in the global SUSTAIN and PIONEER phase III clinical trial programs in a range of clinical settings, including early T2D managed with diet and exercise only, more established T2D uncontrolled on one to three oral antidiabetic drugs, and advanced disease treated with insulin

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