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Regulation of CD8 + T cell-mediated immune responses by amino acid metabolism Glutamine Glutamine is deaminated to form glutamate and -ketoglutarate (-KG), which supports anaplerosis of the TCA cycle and plays a crucial role in regulating histone methylation and chromatin accessibility (Fig

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Olatunji LA, Usman TO, Akinade AI, Adeyanju OA, Kim IK, Soladoye AO (2017) Low-dose spironolactone ameliorates insulin resistance and suppresses elevated plasminogen activator inhibitor-1 during gestational testosterone exposure

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