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This structure binds more tightly to DNA repair proteins than it does to normal double-stranded DNA, making the bulge structures a potential binding site for therapeutic drugs (Pieniazek et al., 2011)

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity

However, the restoration of food intake after surgery by ic ODT8-SST is not secondary to the normalization of circulating acyl ghrelin as the ghrelin receptor antagonist, [D-Lys 3 ]-GHRP-6 injected intraperitoneally (ip) did not alter ic ODT8-SST's action (Stengel et al., 2011b)