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In line with the covalent binding mechanism, in vitro and cell-based thermal-shift assays showed that C1-27 induced a negative shift in the melting temperature indicating protein destabilization on binding (Supplementary Figs 11 and 15)

The gut microbiota contributes to host metabolism and protects against pathogens, thereby affecting directly or indirectly host physiological functions ( Collinsella belongs to the family Coriobacteriaceae and the phylum Actinobacteria

Int J Mol Sci 21:21:5657

Taurine and N-acetyl-L-tyrosine are amino acids that play important roles in neurotransmitter function and cognitive performance, supporting mental clarity and reaction time for demanding tasks such as studying, gaming, or long hours at work