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Wnt proteins are morphogens that elicit a multitude of cellular responses via canonical -catenin-dependent and noncanonical, -catenin-independent signals and the association and release of YAP/TAZ from the -catenin destruction complex have been recently implicated in HSC activation

The study protocol was approved by the Bioethical Committee of the Lower Silesian Medical Chamber in Wroclaw (approval identification number 1/NT/2016 from 10.02.2016)

[14] As the pyridoxine molecule can be gradually degraded by exposure to light, it is advisable to store the vials in their carton or in a light-resistant container to minimize light exposure

Ng HH, Zhang Y, Hendrich B, Johnson CA, Turner BM, Erdjument-Bromage H et al (1999)