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But people who need to regain full mobility and strength of the shoulder will need to get surgery

10.1016/0196-9781(94)90115-5 104 SchmidtB.LindmanS.TongW.LindebergG.GogollA.LaiZ.et al (1997)

Additionally, the smaller size of NPs leads to a larger surface area to volume ratio, which could increase the reactivity of NPs as it has more surface area to interact with cellular components (Johnston et al., 2010)