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They urged people to climb to their roofs to await shelter if water was rising inside their homes, and local television news anchors reminded people to stay out of attics where they might be trapped by rising water or at least bring an ax to hack their way to the roof

Since the sequences are composed of alternating charged polar and non-polar residues, the beta-sheet structure is characterized by a spatial arrangement in which all the non-polar chains align on one face of the beta sheet while all the charged chains (both positive and negative) are on the opposite face of the -sheet

For example, a genetic predisposition may become unmasked in the presence of age-related malnutrition, or changes in neuronal homeostasis

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