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Afanasev IB, Dorozhko AI, Brodskii AV, Kostyuk VA, Potapovitch AI

Slow wall-directed injection prevents both

The (i) initiation stage of tumorigenesis is characterized by increased production of peroxinitrite (ONOO ), superoxide (O 2 ) and hydroxyl ( OH) radicals and hydrogen peroxide (H 2 O 2 ) to accomplish the genetic alterations necessary for independent cellular proliferation