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I.Jurez-MaldonadoA

This function is essential for preserving organelle integrity, particularly in tissues with high energy demands, such as the brain and heart

For NADH-specific quantification, parallel aliquots were heat-treated at 60 C for 30 min to degrade NAD

Other metabolically activated drugs whose P450 inactivation mechanism is not fully elucidated are mifepristone, troglitazone, raloxifene, and tamoxifen