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Dihexa is independently capable of activating the HGF/c-Met system in the adult rat brain alone as well as in conjunction with HGF

Ruff CT, Giugliano RP, Braunwald E, et al

However, when mast cells trigger too easily, they degranulate and release a payload of histamine, heparin, prostaglandins, tryptase, and cytokines into the body too frequently