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In this regard, it has been shown that tamoxifen, a type of selective estrogen receptor modulator (SERM) that acts as a competitive antagonist or as a partial agonist depending on the cell type, favors the repair of demyelinated lesions in the CNS by increasing the mRNA levels of myelin basic protein (MBP) and 2, 3-Cyclic nucleotide 3-phosphodiesterase (CNP), two genes highly expressed during oligodendroglial differentiation (Gonzalez et al., 2016)

While further data is needed to identify dose, frequency, and appropriate age group, intranasal oxytocin may offer some benefit to patients with ASD

High levels of ASCT2 are correlated with aggressive tumor growth and short survival time

Drug Discovery Today: Disease Mechanisms in Press, corrected Proof (2009)