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Depigmentation without dermatologic guidance may increase skin cancer risk, particularly in darker skin tones

Hydrogen peroxide (H 2 O 2 ), the hydroxyl radical, malondialdehyde (MDA), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD), to mention a few, are the key indicators of the body's overall antioxidant capability

These compounds act through modulation of neuroinflammation and oxidative stress by regulating microglial activation and reducing proinflammatory cytokines (Veselinovi et al., 2021)