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10.1126/sciadv.abe0083 126

Brain tissues in hypertensive brain-injured rats exhibited changes in ferroptosis-relevant indicators, such as decreased expression of GPX4, glutathione (GSH), increased iron content and malondialdehyde (MDA)

Meanwhile, vitamin C itself scavenges ROS in aqueous environments, particularly in the cytoplasm and extracellular fluids

FASEB J 18(15):17911800 Mallat Z et al (1998) Elevated levels of 8-iso-prostaglandin F2alpha in pericardial fluid of patients with heart failure: a potential role for in vivo oxidant stress in ventricular dilatation and progression to heart failure