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As an extension of the above, the brains high metabolic rate and oxygen consumption make it vulnerable to oxidative stress, which can lead to aging and neurodegenerative diseases like Alzheimers and Parkinsons Disease

Chem Biol Interact 159(1):1846

Ischemic models can be generated in both small and large animals

Among the most studied agents, N-acetylcysteine (NAC) functions both as a direct ROS scavenger and a precursor for glutathione synthesis, effectively restoring redox balance