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Acknowledgements This work was created as part of NCCR Catalysis, a National Centre of Competence in Research funded by the Swiss National Science Foundation (grant number 180544 to R.M.B) and by AEI (Spain) (grant number RTI2018-099592-B-C22 to G.J.-O)

g , Violin plots showing relative fold change (log 2 ) in IP protein abundance associated with indicated organelles from HEK293T cells expressing ER-tag compared to those expressing control-tag