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The enzymatic activity of -glutamylcysteine synthetase did not change significantly in infested resistant plants (Figure S2)

Heart attacks and strokes account for around 85% of the fatalities listed above

Thus, in alignment with the interpretation from Thomas et al, perhaps changes in cerebrovascular resistance observed in RT are to be separated from vascular pathology and recontextualized as a favourable adaptation, as increased resistance may suppress transmission of pulsatile blood flow into the cerebral circulation during- and post-resistance exercise (Koch et al., 2005)

Similarly, Leucine has been shown to increase the susceptibility of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and activating electron transport chains, thereby increasing reactive oxygen species (ROS) production (Yang et al., 2023)