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Quick answer: L-carnitine is most plausible for people with a real carnitine deficit or a context where trials show bigger effects: older adults, people with overweight or obesity, some metabolic-health populations, dialysis patients under medical care, and athletes using it for recovery over weeks, not days

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Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice [J]

These findings underscore the promising efficacy of CMS121 both in vitro and in vivo , paving the way for Phase I clinical trials in AD therapy (ClinicalTrials.gov, 2022d)