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Poor food choices on tirzepatide produce worse outcomes than on any other weight loss approach because the absolute food quantity is so much lower

The administration of high doses of lipoic acid by injection to rats decreased the activity of two biotin-dependent enzymes by about 30%-35% (122), but it is not known whether oral or intravenous lipoic acid supplementation substantially increases the requirement for biotin in humans (123)

People who eat plant-based diets, take certain medications, or have gastrointestinal issues may struggle to absorb enough

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