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A Role for 12-lipoxygenase in Nerve Cell Death Caused by Glutathione Depletion

Invertebrate animal models Caenorhabditis elegans model The nematode C

Moreover, overexpression of Mtr caused a marked increase in the ratio of reduced to oxidised mycothiol (MSH:MSSM) and significantly enhanced the activities of a variety of antioxidant enzymes, including mycothiol peroxidase (MPx), mycoredoxin 1 (Mrx1), thioredoxin 1 (Trx1) and methionine sulfoxide reductase A (MsrA)