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Targeting glutamate metabolism holds immense potential for enhancing anti-tumor immunity, presenting novel avenues for therapeutic intervention

[DOI] [PubMed] [Google Scholar] Merksamer PI, Liu Y, He W, Hirschey MD, Chen D, Verdin E

The GSH depletion which was observed in the present study [Table/Fig-1] can be caused by acetaldehyde accumulation [32], and increased utilization by the glutathione-S-transferases as well as GGT, the enzymes which are involved in the detoxification of xenobiotics

According to an analysis of the redox balance, sera antioxidant levels were lower in thyroid cancer patients than in healthy controls, and OxS marker sera levels in thyroid cancer patients were significantly higher than in the control samples (119)