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doi: 10.3389/fcell.2021.732820 45 MahajanNAroraPSandhirR

Cuprizone-brain damage and motoric disability The used cuprizone regimen, several times higher than those regularly used in cuprizone studies (62), rapidly induced marked functional disability along with severely affected various brain areas

Aside from this, the only notable difference is that AtDHAR3 is relatively strongly expressed in leaves, which is consistent with its predicted localization to plastids (Figure 4)

We also detected a significant drop in total GSH in ADH5 cells, which might indicate that the active efflux of HSMGSH could contribute to a drop in the net cellular GSH thus also affecting cellular redox homeostasis (Fig