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Golden EB, Chhabra A, Chachoua A, Adams S, Donach M, Fenton-Kerimian M, et al

Abstract Chisholm, A.D

Despite its ubiquity and recognized safety when taken within recommended doses, APAP overdose remains a significant public health concern worldwide due to liver injury, posing a substantial burden on healthcare systems and contributing to a considerable number of hospitalizations and fatalities annually

This pathway begins with the accurate determination of the methylation status of key gene promoters (such as NIS and TSHR) in tumor tissues or circulating tumor DNA (ctDNA) using high-sensitivity techniques such as pyrosequencing or methylation-specific PCR [140, 141]