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2.12.1 Therapeutic investigations BALB/c mice have served as an invaluable model for investigating the therapeutic potential of natural compounds in AD research

Possible Side Effects Short-term use is usually safe, but long-term or high-dose use may cause: Increased appetite or weight gain High blood pressure or high blood sugar Mood changes such as irritability or insomnia Weakening of bones or muscles Higher risk of infections Skin thinning if used too much as a cream Important Advice Never stop long-term hydrocortisone suddenly

Published online December 16, 2021

Dehydration and electrolyte imbalance: Dehydration and depletion of essential minerals such as potassium, magnesium, and calcium can trigger muscle spasms, especially during or after intense physical activity in hot weather