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However, HIROZ primarily triggers the release of zinc ions upon NIR-II photothermal activation, causing a surge in bacterial ROS production and membrane destabilization, ultimately resulting in bacterial eradication and the reinstatement of the pro-inflammatory M1 macrophage polarization

Simultaneous loss of both atypical protein kinase C genes in the intestinal epithelium drives serrated intestinal cancer by impairing immunosurveillance