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Both the cytotoxic effect of A and the impairment of barrier function are partly due to the interaction of A monomers and oligomers with membrane-bound RAGE

doi: 10.1074/jbc.C100109200 15 MahadevKMotoshimaHWuXRuddyJMArnoldRSChengGet al

Anxiety or Vasovagal Response: Sometimes, the experience of getting an IV can trigger anxiety or a vasovagal response, resulting in lightheadedness or nausea