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Simultaneously, half of the livers and gills in all treated groups were fixed in a 10% formalin solution for pathological investigation

Nobiletin , a flavone found in citrus peels, exerted anti-inflammatory effects in TNBS-induced colitis through the downregulation of iNOS and COX-2 expression, restoring barrier function through the inhibition of the Akt-NF-B-MLCK pathway [111]