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Stem cells can divide indefinitely to produce more stem cells, or differentiate to give rise to more specialised cells, such as neural progenitor cells

An increasing body of research indicates that the severity of Alzheimer's disease is more closely associated with pathological features of tau than with A plaques

Individuals with genetic predispositions to Alzheimer disease, those with a history of repeated mild TBI, or people experiencing early subjective cognitive decline might benefit from peptide protocols aimed at maintaining neuronal health before significant degeneration occurs

This reference does not suggest if a nootropic works or not -- but it does explain why it may be categorized as a nootropic, as well as serving as a starting point for additional research