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Overexpression of the human insulin-like growth factor I receptor promotes ligand-dependent neoplastic transformation

However, in the intervention process of ferroptosis, it was found that the application of GPX4 inhibitors could not completely block the occurrence of ferroptosis [18, 19], and some ferroptosis was also found in the process of tumour intervention

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Physiological conditions can induce apoptosis, while external factors such as chemicals, radiation, and viral infections can also trigger this process [135]