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Even in asthmatic patients who develop frequent comorbidities such as chronic rhinitis, sinusitis, atopic dermatitis, and certain food allergies, this Th2 cell-mediated inflammation is observed, given its prevalence in chronic allergic inflammation across multiple sites (Kay 2001)

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It also exacerbates high blood pressure by damaging blood vessels, contributes to cardiomyopathy by altering heart function, and increases the risk of ischemia by obstructing coronary arteries