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During the hypoglycemic period after a meal in GDH-HI patients, the plasma insulin concentrations may be reduced, indicating that high insulin levels are not the only cause of hypoglycemia in GDH-HI patients

When this happens, the condition is called Barretts esophagus

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More importantly, colonization with conventional microbiota during early life (within 14 days after birth) reversed this HPA axis hyperreactivity, but colonization in adulthood had limited effects, suggesting the existence of a critical developmental window, a finding of great guiding importance for early intervention strategies