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Although, strictly speaking, a sodium concentration outside the range of 135-145 mmol/L denotes dysnatremia, clinically relevant hypo- or hypernatremia is mostly defined as a sodium concentration outside the extended normal range of 130-150 mmol/L [59]

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This review also contains numerous recent examples of the use of these two techniques (often in combination with other methods) for characterization of mass and size of individual macromolecular solutes, protein conformational and colloidal stability, nonspecific protein-protein interactions in slightly concentrated solutions, reversible specific associations in dilute solutions, and macromolecular interactions in concentrated protein solutions, as well as analysis of supermolecular assemblies (Minton, 2016)