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Volume 11, Issue 7, 526 535

However, four putative mechanisms may underlie the association between elevated UA and the risk of CVD: association with cardiovascular risk factors, increased oxidative stress, increased inflammatory burden and a direct effect of UA on cellular processes leading to cellular (cardiac) dysfunction and injury

Weve moved beyond the just eat less and exercise more advice that dominated the industry for decades and into a more holistic focus on whole-body health for weight loss