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following combination treatment with the topoisomerase II inhibitors there was an increase in cell proliferation and a decrease in apoptosis

doi: 10.1016/j.jstrokecerebrovasdis.2004.05.001

Gelatinase degradation assay By using a gelatin breakdown assay kit (Abcam, Cambridge, UK), levels of gelatinase activity were assessed in both cell and liver tissue lysates