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[Article] [PubMed]100

Because methylcobalamin is classed as a nutritional supplement and is not a licensed prescription only medicine in the UK, it is not available via the NHS and is being offered more and more by non-healthcare and non-prescribing practitioners as a treatment for wellness, fatigue, and to boost energy, without making any medical claims around deficiency, and is rarely combined with a supplement of adenosylcobalamin

And safety runs through all of it allergies and anaphylaxis, electrolyte and osmolarity considerations, fluid overload in patients with heart or kidney disease, and G6PD screening before any high-dose vitamin C or oxidative therapy

Others need 250mcg to notice anything