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J Stroke Cerebrovasc Dis (2016) 25:111927

In addition, the maintenance of body weight upon infection-associated cachexia in CD8 + T-cell null mice strongly suggest that CD8 + T-cells contribute to skeletal muscle wasting ( + CD44Low nave T-cells reduces muscle atrophy, muscle protein and DNA loss, even when inoculated after the onset of cachexia, associated with a protection from CD4 + T-cell lymphopenia (Wang et al., 2008)