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785,786,787 The FDA has approved this approach for certain diseases

Metabolomics provides a comprehensive analysis of the characteristics and the interaction of low-molecular weight metabolites under specific conditions 3,4,5

We propose a mechanism to better explain the downstream pathophysiological events in AD powered by age-related intracellular aggregation of amyloid- (A) in the vesicular trafficking system initiated by an oxidative shift in redox state that lowers bioenergetic capacity [2, 3]