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Conflict of interest MC has received consulting fees from AstraZeneca, Mallinckrodt Pharmaceuticals, MitogenDx, Werfen, Celltrion, Organon, and GlaxoSmithKline

Methods: We searched PubMed, Embase and Cochrane Library for randomized controlled trials (RCTs) comparing DAPT and aspirin alone to secondary stroke prevention in patients with minor stroke or high-risk TIA