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S-adenosylhomocysteine is a feedback inhibitor of SAM-dependent methylation reactions, and thus hyperhomocysteinemia may affect epigenetic programming as well as other methylation-dependent processes

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Lipoglycometabolism, insulin sensitivity, and plasma glucose regulation are all dependent on it (Smith et al., 2016)

Expression of Osteoprotegerin, Receptor Activator of NFB Ligand (Osteoprotegerin Ligand) and Related Proinflammatory Cytokines During Fracture Healing