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EMT increases reliance on mitochondrial isocitrate dehydrogenase 2 (IDH2)-mediated reductive carboxylation of glutamine for fatty acid synthesis, reducing glycolytic flux and glutathione production

HIV-1 myristoylated Nef treatment of murine microglial cells activates inducible nitric oxide synthase, NO 2 production and neurotoxic activity

This Research Topic is part of a series with: The changing faces of glutathione, a cellular protagonist., Volume II Glutathione (GSH) has been described for a long time just as a defensive reagent against the action of toxic xenobiotics (drugs, pollutants, carcinogens), both directly and as a cofactor for GSH transferases

As your body's master antioxidant, it's a substance your cells naturally produce