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While some facilities or pharmacies may offer lower-priced B12 injections, typically ranging from $15 to $25 per shot, patients should always ensure the injections are administered by qualified, reputable healthcare providers to ensure safety, effectiveness and quality of care

452 Clinically, oral budesonide (9 mg daily) is safe and effective for clinical and endoscopic remission in patients with mild to moderate UC that is refractory to mesalazine

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Acknowledgements We thank Alainaa Refaie and Dessalegn Lamesgen Chnie, who have polished the manuscript