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Beyond its canonical role in mediating vitamin D actions, VDR functions as a direct sensor for specific gut microbiota-derived secondary BAs, notably lithocholic acid (LCA) and its oxidized derivative 3-oxoLCA (105)

10.1016/j.ophtha.2015.08.002 Ophthalmology 69 KaganD

*Correspondence: Lu Han, [email protected] This article was submitted to Microorganisms in Vertebrate Digestive Systems, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

because they respond better to the former) are discriminated against, in that the flawed Section 4 Substance regime is being imposed on them, and they are treated in the same way as users of higenamine, which is (currently) banned at all times