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To this end, the Pmc4 mediator subunit was fused to a degron, and we found that IAA17 in combination with the two F-box proteins atAFB2 and osTIR1 was most effective (Supplementary Fig

12 , e2409344 (2025)

First, under conditions of nutritional ketosis, -HB constitutes the principal KB in systemic circulation, representing the majority of the dynamic range in circulating ketone concentrations

Conclusion This study suggests that innate and adaptive immune cells have distinct distribution profiles in the salivary glandular tissues of patients with pSS and highlights mitochondrial metabolic pathways that may contribute to disease progression