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doi: 10.1016/s0021-9258(17)36700-5 19 KanntARajagopalSKadnurSVSureshJBhamidipatiRKSwaminathanSet al

The compound should not be used continuously without breaks

(Around 8C is usually about the best temperature for storing liquids to maintain molecular compound stability, with temperature stability more important than a specific degree but I only know this from food industry storage best practice and don't readily have the scientific papers to back up what I'm saying